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One of the major contributing factors to poor response is thought to be medication-related issues or polypharmacy, especially in older individuals and those with concomitant illnesses

Methods All mouse experiments were approved by the Animal Ethical and Welfare Committee of the Sixth Affiliated Hospital of Sun Yat-sen University carried out following their legal requirements

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Attia details various supplementation, nutrition, exercise and prescription approaches useful to people in every decade of life to improve vitality, reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health

In addition, magnesium and zinc contribute to normal cell division, while vitamin C and magnesium help reduce tiredness and fatigue

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways