In some embodiments, the otic formulation or composition comprises about 0.07% by weight of the viscosity modulating agent(s)
Molecular Weight:340.87 g/mol
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The role of mitophagy in female reproductive system diseases: from molecular mechanisms to therapeutic strategies
In certain embodiments, tonicity agents are added to the formulations described herein in an amount as to provide a practical osmolality of an otic formulation of about 100 mOsm/kg to about 1000 mOsm/kg, from about 200 mOsm/kg to about 800 mOsm/kg, from about 250 mOsm/kg to about 500 mOsm/kg, from about 250 mOsm/kg to about 350 mOsm/kg, or from about 280 mOsm/kg to about 320 mOsm/kg
Because cysteine is a rate-limiting substrate for glutathione synthesis, we hypothesized that 2-AB reflects glutathione compensation against oxidative stress