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Joglar JA, Chung MK, Armbruster AL, et al

40 Despite NBDHEXs promising anticancer activity, consideration should be given to the relatively low GST-target selectivity and poor water-solubility

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Many biochemical reactions in the human body are enzyme catalyzed reactions, most of these enzymes with thiol as active groups, the state of the thiol group determines the activation and inhibition of enzyme activity

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