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This is not merely additive: the MOTS-c may amplify or extend the mitochondrial biogenesis signal beyond what training alone achieves, particularly in older adults whose endogenous MOTS-c response to exercise is blunted [2]

When administered intravenously, it bypasses digestion and enters the bloodstream directly

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Some MCD biological activity takes different routes and might be an excellent example of the structure-function link (Figure 2)

Bai, Y., Gong, X., Dou, C., Cao, Z