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Monitoring For patients on chronic GHK-Cu: Serum copper and zinc at baseline and periodically Liver function tests in patients on long-duration protocols Clinical assessment of any new neurological or hepatic symptoms Standard compounded-peptide quality and sourcing practices Key Takeaways GHK-Cu is a copper-binding peptide with a generally favorable safety profile

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Altered expression of glutamate transporters, including the cystineglutamate transporter (xCT) system, increases concentrations of extracellular glutamate, which contribute to epileptic discharge, tumour proliferation and peripheral excitotoxicity

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Synthetic lethal screening identifies compounds activating Iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring Cancer cells

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