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Moreover, in an in vitro model of blast-induced auditory hair cell damage, 3-AB inhibition of PARP1 reduced oxidative stress markers, upregulated antioxidant defenses, and helped maintain cell viability by preserving ATP pools 175

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For this reason, cooking food in water with methods like boiling can cause a huge reduction in antioxidant content

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However, chloroquine is shown to result in cardiotoxicity, often in the form of restricted or dilated cardiomyopathy or conduction system abnormalities

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