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Oncogene 19(49):56145619 Dong Y et al (2009) Downregulation of EphA1 in colorectal carcinomas correlates with invasion and metastasis

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Clinical trial design must account for this heterogeneity, possibly incorporating patient stratification based on imaging, genetic risk factors (e.g., APOE or TREM2 variants), or peripheral cytokine profiles

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the cells from tumor and draining lymph nodes tissue were stained with anti-CD11c-PE, anti-CD80-FITC, and anti-CD86-APC antibodies for 30 min, and further analyzed the ratio of mature dendritic cells (DCs)

IGF-1 has also been shown to reduce the toxic effects of NDMA over-stimulation, thereby protecting neurons from excitotoxity, which can lead to neuron death