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Liang, Y., et al

Subcutaneous administration in normal and metabolically dysregulated mice significantly inhibits NNMT activity in metabolically active tissues (adipose, liver, muscle), increases systemic NAD+ levels, enhances mitochondrial function, and improves energy metabolism

Retrieved from Rise Mens Health

Vitamin B12 is a water-soluble vitamin your body uses to make red blood cells, maintain a healthy nervous system, and release energy from food

Therefore, when you take Xenical and eat a food that has fat, it reduces the amount of fat that is absorbed into the body by roughly 30 percent

For people with absorption issues (and most adults over 50 have at least some), oral B12 simply doesnt deliver enough cobalamin to make a felt difference