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As a result, most registered clinical trials aim to extend the therapeutic window of LD/CD while mitigating adverse events

In AD, TNF-, oxidative stress, or microbial cues induce keratinocyte necroptosis, resulting in IL-33 release and ILC2 activation, thereby promoting Th2-skewed inflammation

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Despite inconsistent findings, maintaining an adequate calcidiol concentration is typically viewed as advantageous for maintaining good health [8]

Blask, D

[DOI] [PMC free article] [PubMed] [Google Scholar] 218.Copp J.P., Desprez P.Y., Krtolica A., Campisi J