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AH: Data curation, Formal analysis, Investigation, Validation, Writing original draft, Writing review & editing

The SLC52A2 gene is highly expressed in the brain and mutations in this gene result in the autosomal recessive progressive neurological disorder known as Brown-Vialetto-Van Laere syndrome 2

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Following CI, the interaction between extracellular matrix metalloproteinase inducer and platelet glycoprotein VI can lead to intravascular fibrin deposition and platelet adhesion, and subsequent microthrombus formation (Seizer et al., 2009

It blocks the activity of the enzyme tyrosinase and decreases melanin synthesis