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Indeed, a PUFA-enriched WD containing 10% fish oil (with -3 and -6 PUFAs) evoked focal neutrophilic enteritis in male and female Gpx4 +/IEC mice that was characterized by granuloma-like mucosal to submucosal accumulation of inflammatory cells and expression of the IL-8 homologue Cxcl1

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Medinfo 8 Pt 1:771-5, 1995