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Peer review Peer review information Nature Communications thanks David Relman, and the other, anonymous, reviewer for their contribution to the peer review of this work

Early therapeutic interventions target the temporal duality of MRIS, aiming to mitigate the initial uncompensated glycolytic acceleration (or glycolytic frenzy) by inhibiting lactate dehydrogenase to prevent acidosis [41]

Comprehensive view of macrophage autophagy and its application in cardiovascular diseases

This triggers measurable physiological changes: gastric emptying slows by 7090 minutes, ghrelin rebound is delayed by 46 hours post-meal, and insulin secretion becomes proportional to blood glucose rather than chronically elevated

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Neuroimmunol Neuroinflamm