Compound Name: 5-Amino-1MQ Chemical Classification: NNMT (Nicotinamide N-Methyltransferase) Inhibitor Chemical Name: 5-Amino-1-Methylquinolinium Appearance: White to off-white lyophilised powder Solubility: Typically soluble in bacteriostatic water or sterile research-grade diluents Research Category: Metabolic- and NAD-pathway research compound Common Research Areas: NAD-metabolism investigations NNMT-pathway research Mitochondrial-function studies Metabolic-regulation investigations Glucose- and insulin-related research Healthy-aging and cellular-energy research models Cellular-maintenance and physiological-resilience investigations For Laboratory and Research Purposes Only Not intended for human consumption or therapeutic use
For example, shots given into the muscle are often needed less often than those given under the skin
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Athletes use B12 injections for performance recovery, while older adults benefit from prevention of age-related cognitive decline
In preclinical heart failure models, NNMT enzyme inhibition markedly reduced cardiac 1-MNA (by 77.1%), improved cardiac function, reduced left ventricular hypertrophy and fibrosis, and decreased pro-inflammatory gene expression