doi: 10.1111/1750-3841.13672 361 SinghJPKaurASinghNNimLShevkaniKKaurHet al
Hormonal Changes: Pregnancy, birth control, hormone therapy often trigger melasma
In certain instances, once exposure to an active agent (e.g., concentration in the endolymph or perilymph) reaches steady state, the concentration of an active agent in the endolymph or perilymph stays at or about the therapeutic dose for an extended period of time (e.g., one day, 2 days, 3 days, 4 days, 5 days, 6 days, 1 week, 3 weeks, 6 weeks, or 2 months)
This requires individualized consideration
Unfortunately, Navitoclax is not without flaws
[DOI] [PubMed] [Google Scholar] 73.Varejao A.S., Meek M.F., Ferreira A.J., Patricio J.A., Cabrita A.M