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[PMC free article: PMC5756107] [PubMed: 29018035] 739

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This supplement promotes beneficial estrogen metabolism by increasing 2-hydroxyestrone, a protective estrogen metabolite, while decreasing 16-alpha-hydroxyestrone, a problematic metabolite associated with increased cancer risk

Clinical trials did not identify sleep disruption as an AOD 9604 side effect

Thats where the danger lies

Current research regarding Dihexa focuses on its ability to improve the recovery of peripheral nerve functioning, as well as how the compound interacts with the PI3K/AKT pathway to prompt the procognitive capacity of the nootropic