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Corneal epithelial cells lose the GPX4 shield under hyperosmotic conditions, and lipid ROS rapidly break through the cell membrane and induce corneal opacity

It appeared to lower the intensity of H2AX signalsa marker of DNA damageand seemed to decrease apoptosis rates, as indicated by reduced Annexin-V staining

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[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Costelli P., Muscaritoli M., Bossola M., Penna F., Reffo P., Bonetto A., Busquets S., Bonelli G., Lopez-Soriano F.J., Doglietto G.B., et al

To this effect we tested the well-known calcium ionophore and previously described eryptosis inducer ionomycin (Bratosin et al., 2001

Q5: Can this be combined with other supplements