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The published evidence base is primarily preclinical, so wording should remain as studies have shown in model systems and preclinical research reported

Govt Review] American Journal of Therapeutics

After synthesis, the material undergoes purification through high-performance liquid chromatography (HPLC) , followed by mass spectrometry (MS) verification

TLR2, a key member of the toll-like receptor family, is recognized for its ability to bind various natural ligands and can participate its involvement in the progression of diverse diseases [35, 36]

doi: 10.1038/s41380-022-01792-4 265 MeissnerWGRemyPGiordanaCMaltteDDerkinderenPAnheimMet al

& Luo, H