In recent studies, HLA-A*33:01 was associated with DILI due to ticlopidine (OR, 163.1), methyldopa (OR, 97.8), fenofibrate (OR, 58.7), terbinafine (OR, 40.5), enalapril (OR, 34.8), sertraline (OR, 29), and erythromycin (OR 10.2) in GWASs of persons of European descent
Acta 1851, 10831094
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and in a related condition known as neuromyelitis optica (NMO)
Serious side effects are rare when used under physician supervision with appropriate dosing
(186) showed, using oligofructose as an example, that giving patients with MASH a supplement of the prebiotic can improve their liver steatosis and non-alcoholic fatty liver activity score (NAS) (186)