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Unlike traditional stimulants, it doesnt increase dopamine or adrenaline levels but instead works at a cellular level to help: It has been studied in the context of Alzheimers disease, traumatic brain injury (TBI), and age-related cognitive declinebut is also used more broadly by high-performing professionals and students seeking sharper mental performance

Stem Cells 12 , 12141236 (2020)

However, the use of tamoxifen has been confirmed to be involved in the upregulation of ER36, SPhk1 (sphingosine kinase 1), and S1P (sphingosine-1-phosphate), which further activates downstream signaling pathways and causes drug resistance ( Protein arginine N-methyltransferase 2 (PRMT2

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Numaga-Tomita T, Nishida M (2020) TRPC channels in cardiac plasticity

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