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Even with adequate dietary intake of vitamin B12, poor absorption in the gut can still lead to vitamin B12 deficiency. Taking vitamin B12 as an oral supplement is largely a waste of money

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Tirzepatide (Mounjaro/Zepbound) and Semaglutide (Ozempic/Wegovy) are the interventions that have demonstrated clinically meaningful, sustained fat reduction across large patient populations

Ice-crystal formation during each freeze-thaw cycle inflicts mechanical damage on peptide chains, and pre-splitting eliminates the cumulative loss that comes from thawing one vial multiple times

Intramuscular shots put B12 right into the muscle

Some compounders claim adding B12 to a GLP-1 may help address fatigue, particularly in people with a vitamin deficiency