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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Das S., Seth R.K., Kumar A., Kadiiska M.B., Michelotti G., Diehl A.M., Chatterjee S

4.4 Biological heterogeneity and value assessment Even if manufacturing and safety hurdles are overcome, the biological heterogeneity of the tumor microenvironment remains a central challenge for the clinical and economic value of TME-oriented nanoplatforms [67, 115]

LC transporter ( SLC7A10 ) mRNA in adipose tissue shows a strong inverse correlation with IR, adipocyte size, and metabolic syndrome components, along with a strong heritability and an association with type 2 diabetes risk alleles

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Whether through modulating central glycolytic pathways, disrupting redox homeostasis, or reshaping transcriptional programs, their functions extend well beyond the classical roles of conventional enzymes

Drawing upon decades of clinical experience and digital innovation, Dr