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This dual failure to clear both ectopic tissue and senescent cells creates a permissive environment for the chronic inflammation that characterizes endometriosis

however, the 5-year survival rate for patients with advanced OC remains low (49%, 2022) due to tumor heterogeneity, lack of reliable early diagnostic methods and the high incidence of chemotherapy resistance

Hou L, Zhu ZZ, Zhang X, Nordio F, Bonzini M, Schwartz J, et al

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2008, 294: L478-L488

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