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TB 500 has been the subject of some more controversy than BPC 157, however

doi: 10.1038/s41579-022-00720-1 125 FisherM

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the KYDN neurons and then GnRH-secreting neurons) (25), the positive improvement of the metabolic impairment is probably not the only one needed to re-activate a normal reproductive profile, given that no significant changes in plasma LH concentrations were observed during the 6 months of treatment