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Pure water contains both hydrogen and hydroxide ions at concentrations of 107 mol/1

The non-negotiables are strict broad-spectrum SPF 30 or higher daily, conservative initial cadence (start with monthly rather than bi-weekly), patch testing on the jawline first, and avoidance during active flare

Porous silicon NPs can be oxidatively hydrolyzed in aqueous solution under physiological conditions, and its degradation product, silicic acid, is non-toxic and excreted in the urine[131]

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Bleeding time assessment was performed using the Surgicutt device (ITC, Edison, NJ, USA) according to the manufacturers instructions

HEK293T cells were transfected with 1 g lentiCRISPRv2 containing the sgRNA insert, 0.67 g psPAX2 (Addgene, 12260) and 0.33 g pVSVg (Addgene, 8454) using 6 g polyethylenimine (Sigma-Aldrich, 919012) in Opti-MEM (Thermo Fisher, 31985062)