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The primary endpoint was NIHSS at admission and the secondary endpoints were discharge NIHSS, mRs at 3 months, and in-hospital and 3-month mortalities

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MEDI7247, an antibody-drug conjugate (ADC) that specifically binds to the extracellular domain of ASCT2, could release its payload pyrrolobenzodiazepine (PBD), promoting DNA damage and tumor cell death (Liu et al., 2018