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at the same time, since the intracerebral hematoma releases hemoglobin (Hb)-based neurotoxin (Wang 2010), the neural damages secondary to perihematomal edema (PHE) that is caused by BBB disruption also occur in the brain parenchyma, becoming an important cause of morbidity and mortality in patients (Jeon et al., 2021)

(Source 3) 6

Journal of Clinical Oncology , 27 (31), 51245130

The receptor is now recognized as a promising target for modulating neuroinflammation and microglia-mediated neuronal survival, particularly following the discovery of A 2A receptor upregulation in microglia from the prefrontal cortex of AD patients [483]

Frequency: 1-2 cycles per year for longevity benefits

In addition, the brain is rich in polyunsaturated fatty acids and a significant level of damage originates from lipid peroxidation and oxidative products such as carcinogenic 4-hydroxynonenal and potentially mutagenic malondialdehyde (Liu et al