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Funding JB is supported by funding from the United Kingdom Medical Research Council Clinician Scientist Fellowship MR/T008024/1 and NIHR Great Ormond Street Hospital Biomedical Research Centre

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At the 5mg dose, 85% of participants lost at least 5% of their body weight

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This selectivity is crucial because many methyltransferases play essential roles in neurotransmitter metabolism, gene expression, and protein function