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Clinical research confirms that 1000 mg NR doses twice daily can boost steady-state, whole-blood NAD+ levels up to 2.7-fold after one dose [4]

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Lequeux, I., Ducasse, E., Jouenne, T., and Thebault, P., Eur

Blood should be collected fasting, centrifuged promptly, and stored at -80C for optimal stability

Nuclear Transcription Factor Activation: Tracking the stimulation of native, cell-autonomous cytoprotective loops and anti-oxidant responses responsible for re-establishing immune homeostasis

J Clin Invest 123(10):45134524 Huang L, Yan M, Kirschke CP (2010) Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription