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Similarly, in pancreatic ductal adenocarcinoma (PDAC) and NALM-6 leukemia cells, membrane lipid remodeling involving polyunsaturated fatty acidcholesterol esters (PUFA-CEs)generated via the acyl-CoA synthetase long-chain family member 4 (ACSL4)sterol o-acyltransferase 1 (SOAT1) pathway and regulated by solute carrier family 47 member 1 (SLC47A1)drives ferroptotic sensitivity [59]

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TPO, thyroid peroxidase

Whats more, the ablation of PKM2 inhibited IL-1-induced the secretion of nitric oxide (NO) and prostaglandin E2 (PGE2), thereby alleviating chondrocyte apoptosis and inhibiting the inflammatory response of chondrocytes

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Effect of Coffee Consumption on Non-Alcoholic Fatty Liver Disease Incidence, Prevalence and Risk of Significant Liver Fibrosis: Systematic Review with Meta-Analysis of Observational Studies