[149] Given the suggestion of the inability of most cell types to take up exogenous glutathione, [144] decreased chemotherapy efficacy due to glutathione administration may be limited to liver, kidney, and neurological tumors
Excessive production of reactive oxygen species can damage the GI mucosa by promoting lipid peroxidation, altering cellular proteins and DNA, impairing mitochondrial function, and triggering apoptosis
Specifically, IKE exerts anti-cancer activity by inducing lipid peroxidation and upregulating ferroptosis genes, including SLC7A11 (73)
R.ChaudharyS.NimmakayalaR
Another recent study developed an innovative biomimetic nanomedicine for GBM treatment, featuring a pH-sensitive polymer core and a shell disguised with GBM cell membranes
Diese Reaktionen treten hufiger im ersten Jahr auf, vor allem unter Infliximab, dann unter Etanercept und vorwiegend bei Patienten mit rheumatoider Arthritis