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Glutathione also helps to support immune function

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This also highlights the need for consideration of haem source in in vitro models, where free haem is typically added as the sole source in culture media: a condition which may not reflect predominant sources in the respiratory and middle ear niches

No tolerance development appears to occur, unlike many pharmaceutical compounds

Although iron levels do not increase during ferroptotic cell death, an increase in cellular iron could increase the vulnerability of cells to cell death