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Anti-estrogen-based endocrine therapies, such as the ER modulator Tamoxifen, ER degrader Fulvestrant, and the aromatase inhibitor Letrozole, have significantly enhanced the survival rates of patients with hormone receptor-positive (HR+) breast cancer [5]

Fazary AE, Ju YH (2007) Feruloyl esterases as biotechnological tools: current and future perspectives

The systems were then heated for 100 ps by incrementing the temperature from 0 to 300 K under a constant pressure of 1 atm and periodic boundary conditions with a timestep of 1 fs

Some other research discovered that enhanced serotonin metabolism may also contribute to decreased central serotonin levels following gut dysbiosis (173)

Cancer stem cells: advances in knowledge and implications for cancer therapy