CBS is a key enzyme in the transsulfuration pathway mediating Ctt and H 2 S production, and CDO1 is a critical enzyme in taurine synthesis, as well as maintenance of the hepatic intracellular free cysteine range
But its cling to fame is its skin lightening ability
This metabolic perturbation further indicated that elevated ROS levels upon GGCT suppression contribute to TCA cycle dysfunction
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Systemic inflammatory response syndrome (SIRS) following unregulated IV administration, presenting with fever above 41 degrees Celsius, acute liver injury, and clotting abnormalities, is also documented in a 2025 case report