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Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine

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This mitochondrial impairment further compromises bone formation capacity, thereby exacerbating skeletal fragility and contributing to osteoporotic progression ( 3.4 Hormone regulation and OP 3.4.1 Estrogen deficiency Estrogensincluding estradiol, estriol, and estroneregulate bone metabolism through both direct and indirect mechanisms mediated by estrogen receptors (ERs), primarily estrogen receptor alpha (ER), which plays a predominant role in this process

Weeks 9 through 12: GHK-Cu 2mg subcutaneous injection every other day

Next, 1 ml chloroform (CHCl 3 ) was added to remove the unreacted dansyl chloride