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some may respond within 15 minutes at higher doses [9] These medications work by enhancing nitric oxide-mediated relaxation of penile smooth muscle, facilitating increased blood flow during sexual stimulation

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These medications, which include semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), act like the bodys own GLP-1 hormone, but in doses much larger than the body produces, to regulate insulin and blood sugar, decrease appetite, and slow down stomach emptying