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[DOI] [PMC free article] [PubMed] [Google Scholar] Sternberg P, Jr, Davidson PC, Jones DP, Hagen TM, Reed RL, Drews-Botsch C

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Differences in data preprocessing and cohort characteristics can affect model stability, while the black box nature of deep learning algorithms limits clinical acceptance

ROS level regulation and cell metabolism both affect ferroptosis, and both processes are influenced by heat stress: when increased iron uptake or decreased storage causes iron overload, free iron generates ROS via the Fenton reaction, directly triggering ferroptosis-related damage

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