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Endogenous redox sensors ( e.g

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doi: 10.3390/molecules24030408 602 RowlandIGibsonGHeinkenAScottKSwannJThieleIet al

These species contribute to oxidative and nitrosative stress by promoting protein nitration and nitrosation reactions, thereby affecting enzyme activity and cellular signalling pathways

For instance, demethylzeylasteral (DML) has been shown to suppress liver cancer stem cell tumorigenicity by inhibiting H3K9la and H3K56la, while royal jelly acid (RJA) inhibits tumor invasion, migration, proliferation, and apoptosis in HCC by targeting H3K9la and H3K14la

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