Eur J Pharmacol (2016) 778:4455
Epitalon (Epithalon) dosage protocols center on this synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from pineal gland research for its geroprotective potential [1]
Fatigue and mild flu-like symptoms can occur, particularly early in treatment
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Holtman IR, Raj DD, Miller JA, Schaafsma W, Yin Z, et al
So, often, the progression of the research went something like this: Start with a crude organ extract Observe biological effects Isolate the smallest peptide sequence responsible Synthesize it Thats actually a very reasonable scientific approach