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Trial Population69mg/wk Starts at 1 mg and builds slowly through 4 mg before increasing

Treatment should not be delayed pending test results if neurological features are present

When to seek medical advice: Persistent or worsening injection site reactions (increasing redness, warmth, or discharge suggesting infection) Severe or persistent headaches Chest pain or palpitations Unexplained muscle weakness or cramps New or worsening neurological symptoms despite treatment Unexpected bleeding or bruising For non-emergency concerns, contact your GP or NHS 111

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How a researcher divides it depends entirely on reconstitution