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18th World Congress of the World Society of Cardio-Thoracic Surgeons, 2008

BPC157 was added at concentrations of 5, 10, 20, and 40 g ml-1 for the indicated periods

The PI3K/AKT/mTOR pathway was recently showed to reduce oxidative stress and promote cell survival of breast epithelial cells segregated from the ECM by strengthening flux through the oxidative PPP (195) PIK3CA mutation, which leads to increased PI3K activity, is the most common somatic mutation in breast cancer, and 36% of patients with HR+/HER2- breast cancer are PIK3CA mutated (196)

Chu, C.X