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When GSH is depleted and GPX4 is inactivated, cells are unable to repair lipid peroxidation damage, and ferroptosis occurs

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G6PD activator AG1 Based on 10 publication(s) in Google Scholar G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) agonist with an EC50 of 3 M