But having a low B12 level or a vitamin B12 deficiency can cause physical, neurological and psychological issues
The research rationale established by NNMT-knockdown studies in diet-induced-obese mice is that inhibiting NNMT preserves intracellular NAD+ and SAM levels, which in adipocyte (fat-cell) models has been shown to suppress de novo lipogenesis
Illnesses Any illness or condition that affects the digestive system can result in a B12 deficiency because the vitamin is bound to the protein molecules in your food and is released and absorbed by the body during digestion
Post-Bariatric Surgery and Malabsorption Syndromes People who have had bariatric surgery or have malabsorption syndromes cant absorb vitamin B12 well
Impaired sensitivity of adipocytes to insulin signaling, including the antilipolytic effects of this hormone, may contribute to enhanced basal lipolysis in obesity
Research involving multiple metabolic-, mitochondrial-, or stimulant-related compounds may warrant additional caution and individualized evaluation in experimental settings
