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Understanding: The menstrual cycle is controlled by negative and positive feedback mechanisms involving ovarian and pituitary hormones The menstrual cycle describes recurring changes that occur within the female reproductive system to make pregnancy possible Each menstrual cycle lasts roughly one month (~28 days) and begins at puberty (menarche) before ending with menopause There are two key groups of hormones which control and coordinate the menstrual cycle: Pituitary hormones (FSH and LH) are released from the anterior pituitary gland and act on the ovaries to develop follicles Ovarian hormones (estrogen and progesterone) are released from the ovaries and act on the uterus to prepare for pregnancy Menstrual Hormones Flowchart of Hormonal Actions During Menstrual Cycle Key Events in the Menstrual Cycle There are four key events that comprise a typical menstrual cycle: follicular phase, ovulation, luteal phase and menstruation These events are distinguished by changes to hormonal levels, follicular development and the status of the endometrium 1

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