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59,70,103,104 In contrast, treatment with NAD + precursors, as well as other forms of energy consumption, such as through exercise, caloric restriction, fasting, and low glucose availability, can counteract aging effects by upregulating NAMPT, which can reconstitute NAD + levels and promote sirtuin activation

doi:10.1007/s10815-017-1032-1

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3.4.2 Adverse effects of meglitinides Repaglinide and nateglinide studies have revealed different levels of hypoglycemia and, overall, lesser weight gain than sulfonylureas (149, 152163)

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Identification of a p53-dependent negative response element in the bcl-2 gene