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Given the inherent limitations of spontaneous reporting systems, potential residual confounding, and insufficient sample sizes for certain agents, the present analysis should be regarded as exploratory

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Sarker M.N.I

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Hepatotoxicity induced by APAP is mainly caused by the production of N-acetyl-p-benzoquinone imine (NAPQI), a highly reactive intermediate formed predominantly via the cytochrome P450 2E1