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Sertraline or imipramine significantly decreased the immobility time in cannabis-treated mice by the day 16 and 18 of the study, respectively

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One preclinical study (Valdecantos et al., ADA 2024) showed combination benefit in obese rats

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Nevertheless, key limitations persist ( Furthermore, while implanting a small number of transplanted cells (around 100200 per embryo) can ensure successful engraftment, it may not necessarily include cancer-driving stem cells, which are indicative of the genetic diversity present in human tumors

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