Systemic glutathione depletion, combined with elevated ROS, damages the endothelial lining of the blood vessels
M., Keov, P., Mariam, Z., Deganutti, G., Christopoulos, G., Hick, C
In a 2023 review, inositol supplementation was described as an effective and safe treatment in PCOS, with outcomes comparable to metformin in some cases.5 L-Methylfolate (500mcg): Folate has been shown to positively affect glycemic, inflammatory, and oxidative stress markers in women with PCOS.7 It may also support fertility and reproductive outcomes, particularly when combined with other nutrients.67 Wholesome Story uses L-methylfolate (MTHF), the biologically active form of folate, which does not require conversion in the body and is often chosen in reproductive-health formulations.86 Vitamin D3 (1,000 IU): One additional consideration is dosing flexibility
It is common for an intramuscular injection of vitamin C to sting during an injection, and afterward have redness, swelling and soreness at the injection site
Psychologically, the constant monitoring of blood glucose levels, adherence to strict dietary restrictions, and regular antidiabetic medication or insulin use contribute to considerable psychological stress and can lead to anxiety and depression [114, 115]
