Decrease dose consideration: Persistent side effects including headaches, fatigue, or injection site reactions, excessive response (extremely rapid weight loss suggesting dose may be higher than needed), cost concerns when lower doses might achieve similar results
In cells depleted of GSH, p16 expression was significantly decreased by rapamycin and increased by 3-MA and Baf-A1 (Fig
The use of Glutathione IV goes beyond just detoxification
Starting with GHK-Cu alone allows assessment of baseline response before adding complexity and cost
There are many mediators released from mast cells, not limited to histamine and tryptase, though these can be measured more readily
ERK1/2, Extracellular Signal-Regulated Kinases 1 and 2