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Description

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Therapeutics targeting mitochondria-associated membranes (MAMs) and lysosomes simultaneously may offer a comprehensive and effective strategy for the treatment of cardiovascular disease

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Moreover, tumor cell-derived exosomes genetically engineered to express a pH-sensitive fusogenic GALA peptide (WEAALAEALAEALAEHLAEALAEALEALAA) efficiently delivered tumor antigens to the cytoplasm of DCs and promoted the tumor antigen presentation of DCs via the major histocompatibility complex class I molecule 38

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In a briefing document released prior to the panel discussion, the FDAs internal reviewers said that Ocaliva had failed to demonstrate efficacy in one of its confirmatory trials

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10.7164/antibiotics.57.337 130 LinJ.YuJ.ZhaoJ.ZhangK.ZhengJ.WangJ.et al (2017)

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