Dit product is bestemd voor onderzoekers en laboratoria die een stabiel, goed karakteriseerbaar peptide zoeken voor in-vitro- en preklinisch werk rond weefsel-, pees- en maag-darmprocessen
Cysteine is described in nutritional literature as conditionally essential meaning it is not strictly essential (the body can produce it from methionine, another sulphur-containing amino acid) but the production pathway has limits, and dietary cysteine remains relevant
Am J Clin Nutr 98:11701178
Two of the three structurally related compounds (afamelanotide and bremelanotide) reached FDA approval in 2019 for narrow orphan or single-indication uses
For example, general control nonderepressible 2 (GCN2) is activated by amino acid starvation, whereas protein kinase-like endoplasmic reticulum kinase (PERK) is activated by endoplasmic reticulum (ER) stress 15
The lipid cofactor-binding sites were found in the AHs of few fission-inducing proteins: PtdIns(4,5)P 2 -binding site in epsin (Kweon et al., 2006